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Isshi-100 Manga Infobox
Japanese Name: イッシー100(ワンハンドレッド)
Romanized Name: Isshī Wan-handoreddo
Official English Name: 100 Doctors (Viz)
100 MDs (FUNimation)
First Appearance: Isshi-20: Chapter 136; Episode 82
Isshi-100: Chapter 637 (cover)
Affiliations: Sakura Kingdom; Wapol Pirates (former); Drum Kingdom (former)
Occupations: Doctors
Leader: Kureha
Residency: Sakura Kingdom
Status: Active

The Isshi-20 were the twenty most skilled doctors on Drum Island, whom Wapol took for himself in order to make his subjects dependant on him for their services.

The Isshi-100 are the Isshi-20 renamed two years after their introduction, as they have found eighty additional doctors, becoming a group of one hundred doctors.


They are one hundred different doctors who dress in scrubs with sunglasses. They constantly have surgery mask and gloves on them. They are all of varying height with similar builds and most of the time stand as if prepared for surgery. The Isshi-20 from two years ago are wearing pink scrubs, but the color for the scrubs the Isshi-100 are currently wearing remains unconfirmed.

Abilities and PowersEdit

The Isshi-20 were skilled enough to save Wapol's life even after he has been decapitated.[1] As the Isshi-100, their individual capabilities as doctors has not yet been delved into.


Service Under WapolEdit

Isshi 20

The Isshi-20, under Wapol's command.

During King Wapol's Doctor Hunt, he ordered all doctors on Drum Island to live under his direct command, while eliminating those who do not comply either by banishment or killing. This was done to force the citizens to grovel Wapol for medical help, so his tyrannical rule would be unopposed.

The twenty doctors who complied became known as the Isshi-20, and while they remain under Wapol's control, they secretly despised and hated him as the rest of the people did. However, they gave in to the king in order to continue their research and refine their techniques. Upon seeing the rogue doctor Dr. Hiluluk's noble sacrifice, the Isshi-20 became determined to never lose to him again. To this end, they hoped to use their research and techniques to help their compatriots. When Wapol fled the kingdom from a fearsome enemy's attack, he took the Isshi-20 with him.[2]

After Wapol was defeated, they were forgiven by the people of the island and rejoined them as citizens of the new Sakura Kingdom.

Service to the Sakura KingdomEdit

Two years later, the Isshi-20 has grown to become the Isshi-100, working for Kureha at Sakura Kingdom's medical center.[3]

They now have a new logo; a black flag combining the cross from Chopper's hat with a silhouette of what looks like Hiluluk's hat.

Translation and Dub IssuesEdit

"Isshi" is derived from "Ishi" (医師), which means "doctor". In the English version, the Isshi-20 are accurately translated as "doctors" or "MDs", meaning medical doctor.


  1. One Piece Manga and Anime - Vol. 15 Chapter 136 and Episode 82, The Isshi-20 save Wapol's decapitation with rapid surgery.
  2. One Piece Manga and Anime — Vol. 15 Chapters 133134 and Episode 80, Dalton explains how Wapol and his men abandoned Drum when the Blackbeard Pirates attacked.
  3. One Piece Manga - Vol. 64 Chapter 637, Kureha and the Isshi-100 are reintroduced.

Site NavigationEdit

[v · e · ?]
Wapol Pirates
Members: Wapol  •  Chess  •  Kuromarimo  •  Chessmarimo  •  Isshi-20  •  Robson  •  Musshuru (non-canon)
Ship(s): Bliking
Devil Fruit Based: Baku Baku no Mi  •  Noko Noko no Mi (non-canon)
Weapon Based: Royal Drum Crown 7-Shot Bliking Cannon
Related Articles
Story Arc: Drum Island Arc
Movies: Episode of Chopper Plus: Bloom in Winter, Miracle Sakura
Locations: Drum Island
[v · e · ?]
Drum Island
Citizens: Former King   •  Dalton  •  Kureha  •  Hiluluk  •  Tony Tony Chopper   •  Negikuma Maria  •  Stool  •  Tamachibi  •  Isshi-100  •  Wapol   •  Chess   •  Kuromarimo   •  Robson *  •  Musshuru  
Devil Fruit Based: Baku Baku no Mi  •  Ushi Ushi no Mi, Model: Bison  •  Hito Hito no Mi  •  Noko Noko no Mi
Related Articles
Locations: Drum Castle  •  Bighorn  •  Cocoa Weed  •  Gyasta  •  Robelle  •  Drum Rockies
Misc: Sakura Kingdom  •  Drum Ropeway
Story Arc(s): Drum Island Arc  •  Post-Enies Lobby Arc  •  Post-War Arc
Movies: Episode of Chopper Plus: Bloom in Winter, Miracle Sakura
[v · e · ?]
Canon: Nako  •  Crocus  •  Kureha  •  Hiluluk  •  Tony Tony Chopper  •  Isshi-100  •  Ho  •  Potsun  •  Muret  •  Doc Q  •  Kurotsuru  •  Kyukyu  •  Hogback  •  Trafalgar D. Water Law  •  Belladonna  •  Fishbonen  •  Aladdin
Non-Canon: Zabal  •  Kobato  •  Nightin

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