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Horu Horu no Mi

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The Horu Horu no Mi is a Paramecia-type Devil Fruit that grants the user the ability to create and control special hormones that can affect anyone they strike by however the user desires, making the user a Hormone Controlling Human (ホルモン自在人間 Horumon Jizai Ningen?).[2] It was eaten by Emporio Ivankov.


  • "Horu" is short for "horumon" (ホルモン?), the Japanese way of pronouncing the word "hormone".
  • In the Viz Manga, FUNimation subs and dub, it is called the Horm-Horm Fruit, shortening the word "hormone".

Strengths and WeaknessesEdit

The major strength of the fruit, as demonstrated by Iva, is to create and manipulate special hormones. These hormones can manipulate various aspects of a person such as gender, body temperature, pigmentation, growth, and even emotional state. The hormones can also be used to greatly increase a person's battle capabilities through healing and energizing. By turning four of their fingers into syringes and stabbing a person, the user is able to inject these hormones and change the person on a genetic level to whatever the user desires. This process can also be used by the user on themselves to aid them. The fruit is unable to penetrate Devil Fruit users who can harden their bodies.[citation needed]

Other than that, the fruit seems to have no other weaknesses outside the standard Devil Fruit weakness.[3]


The fruit's bestowed hormone powers, as used by Iva, have been used for a variety of reasons. Iva seems to enjoy playing around with the concept of "gender" as he and his ally Inazuma are seen switching in and out their male and female forms. In addition, supposedly all the Newkamas of level 5.5 have switched sexes. Though Iva enjoys playing around with his powers, they can also make him a powerfully persistent opponent in battle. Iva has clashed with the likes of Akainu and Magellan and has come out of these battles with little harm, despite the deadly abilities of both opponents. Iva's quick recoveries can be assumed to be due to his ability to greatly heal and energize his body through hormones.

The fruit's powers are the source of Ivankov's "miraculous" reputation, which, aside from gender changing, allow Iva to perform other miracles on people besides himself such as extreme healing, using them to allow for a body to adjust from a fatal-condition to having a chance of survival. However, while he can make the adjustment within the body to heal from these conditions, the miracle is also dependent on the person hit by the altering hormones, whereas only those with a strong enough will can survive and use their survival instincts via the hormones to their advantage. Depending on what the conditions the patient is in, as well as the hormones used, the receiver may suffer a shortening of lifespan in exchange for a "cure".

The named techniques that are used by Emporio Ivankov that involve the Devil Fruit are as follows:

Emporio Onna Hormone

Emporio Onna Hormone.

  • Emporio Onna Hormone (エンポリオ・女ホルモン Enporio Onna Horumon?, literally meaning "Emporio Female Hormone"): By injecting a male with special female hormones, Iva is able to transform them completely into a female. In the Viz Manga, this is called Emporio Estrogen, and in the FUNimation dub it is called Emporio Female Hormone. This was first seen being used on Bellett who was trying to get revenge on Iva.[1] He can also use this on himself, doing so when he fights Sadi.
    • In addition, Iva was able to transform himself and other women (supposedly) into men, but this usage for his ability is not a named technique. It appears that this technique does not affect the clothes of the user as every time someone is hit with this technique their physical appearance changes, but their clothes seem to remain but as appearance is changed, their clothes may be too small or big for them.
  • Emporio Chiyu Hormone (エンポリオ・治癒ホルモン Enporio Chiyu Horumon?, literally meaning "Emporio Healing Hormone"): By injecting special hormones meant to release the body's immune system's full potential into a sick person, Iva is able to cure them. This is the secret to his "miracle" healing. Since the hormones only unleash the immune system's potential, the chance of survival is mostly based upon the individual's will to live. In order to use this technique, a certain amount of the target's life-span must be sacrificed in order to compensate for the energy used to heal the damage. In the case of Luffy's injuries, it took 10 years of his life-span. In the case of things like poison it seems to make them immune to the very ailment that plagued them. In the Viz Manga, this is called Emporio Healing Synthesis, while in the FUNimation dub it is called Emporio Healing Hormone. This was first seen being used on Luffy to counteract Magellan's poison.[4]
  • Emporio Tension Hormone (エンポリオ・テンションホルモン Enporio Tenshon Horumon?): By injecting special adrenaline affecting hormones, Ivankov can provide a tired person with a supply of adrenaline that can relieve tension and allow for easier movement for an entire day. There is an aftereffect after being injected with this hormone, which causes the user to feel nausea and tired. There is a limit to how much fatigue the hormones can relieve, as Ivankov warned Luffy that he would not be getting up again after receiving a second dose. This is called Emporio Energy Synthesis in the Viz Manga and Emporio Energy Hormone in the FUNimation subs and dub. This was first seen being used on an exhausted Luffy.[5] Ivankov has also used this together with Emporio Healing Hormones to recover quickly from fatal poisoning.[6]
Face growth hormone

Emporio Ganmen Seicho Hormone.

  • Emporio Ganmen Seicho Hormone (エンポリオ・顔面成長ホルモン Enporio Ganmen Seichō Horumon?, literally meaning "Emporio Face Growth Hormone"): By injecting special face manipulating hormones, Ivankov can make a person's face expand to enormous proportions that surpass even giants. This is called Emporio Face Growth Synthesis in the Viz Manga and FUNimation subs and dub. This was first seen used by Ivankov on himself during the escape from Impel Down level 4 to make his Death Wink technique into a more powerful version called Hell Wink.[7] While his head is in this state, it allows his hair to hold up to at least 235 people inside it.[8]

Anime and Manga DifferencesEdit

  • In the manga, Ivankov forced a guard to show him where Ace's cell was. In the anime, he used his Emporio Onna Hormones to turn the guard into a woman and persuaded her to tell him where the cell was.
  • In the anime version of his confrontation with Akainu, Ivankov used his syringe needles as slashing weapons in conjunction with his Newkama Kenpo.

Translation and Dub IssuesEdit

The Devil Fruit's gender changing hormones were first seen being used on a male prisoner. In the magazine serialization of the Viz Manga, when the guy was changed into a girl, a top was added to her for censorship reasons despite the guy appearing shirtless earlier.


Straw Hats' Genders Swapped

The Straw Hats genderswapped.

  • In a SBS, a fan asked Oda if he would draw the Straw Hats as they would if they were genderswapped by Iva's hormones. In response, Oda provided the following drawings. For the male crewmembers turned female, they would use a typical Japanese feminine style of talking. The opposite is also said for the female crew members with them using a typical Japanese masculine style of talking. Female Luffy is apparently a vegetarian. Female Zoro apparently does not like putting a sword in her mouth as it would chip her teeth. Female Sanji's specialty would be sweets. For most of the Straw Hats, the genderswap is very apparent. Brook however is not so apparent since he has no flesh to help identify whether he was injected with Iva's gender changing hormones or not.[9]
  • This power is an exaggeration, but not complete fabrication, of what hormones actually can do. Hormones really do control many biological functions in the body, including (but not limited to) growth, behavior, energy, and secondary sex characteristics.


  1. 1.0 1.1 One Piece Manga and Anime — Vol. 55 Chapter 537 (p. 16) and Episode 439, Iva turns a guy into a girl.
  2. One Piece Manga and Anime — Vol. 55 Chapter 538 (p. 8) and Episode 440, Ivankov explains his Devil Fruit ability.
  3. One Piece Manga and Anime — Vol. 57 Chapter 557 (p. 7) and Episode 466, Ivankov falls into the water along with other Devil Fruit users.
  4. One Piece Manga and Anime — Vol. 55 Chapter 538 (p. 3) and Episode 439, Iva injects Luffy with Healing Hormones.
  5. One Piece Manga and Anime — Vol. 55 Chapter 539 (p. 13) and Episode 441, Iva injects Luffy with some Tension Hormones.
  6. One Piece Manga and Anime — Vol. 56 Chapter 549 (p. 4) and Episode 452, Ivankov states that he recovered from Magellan's poison using a combination of healing and tension hormones.
  7. One Piece Manga and Anime — Vol. 55–56 Chapters 541542 and Episodes 444445, Iva makes his face huge to use Hell Wink.
  8. One Piece Manga and Anime — Vol. 56 Chapter 548 and Episode 451, Iva's afro hosts most of the 241 escapees of Impel Down.
  9. SBS One Piece MangaVol. 56, Fan Question: Would you draw the Straw Hats genderswapped?

External linksEdit

  • Hormones - Wikipedia entry on hormones.
  • Endocrine System - Wikipedia article on the body system that produces hormones.
  • Genetic Engineering - Wikipedia article on the Ivankov's main Devil Fruit ability.
  • Sex Change - Wikipedia article on Ivankov's main use of his Devil Fruit.
  • Adrenaline - Wikipedia article on adrenaline, one of the many hormones Ivankov can control.

Site NavigationEdit

[v · e · ?]
Okama: Bentham  •  Emporio Ivankov  •  Inazuma  •  Tibany  •  Splash and Splatter  •  Caroline
Former: Sanji
Devil Fruits Based: Mane Mane no Mi  •  Horu Horu no Mi  •  Choki Choki no Mi
Fighting Styles Based: Okama Kenpo  •  Newkama Kenpo
Related Articles
Locations: Momoiro Island  •  Newkama Land
Story Arcs: Alabasta Arc  •  Impel Down Arc  •  Post-War Arc
[v · e · ?]
Revolutionary Army
Current Members: Monkey D. Dragon  •  Sabo  •  Emporio Ivankov  •  Inazuma  •  Terry Gilteo  •  Bunny Joe  •  Koala  •  Hack  •  Raise Max 
Former Member(s): Bartholomew Kuma
Associate(s): Nico Robin
Devil Fruit Based: Horu Horu no Mi  •  Choki Choki no Mi  •  Nikyu Nikyu no Mi  •  Mera Mera no Mi  •  Hana Hana no Mi
Fighting Style Based: Newkama Kenpo  •  Fishman Karate  •  Haki  •  Fishman Jujutsu  •  Ryusoken
Related Articles
Story Arc(s): Loguetown Arc  •  Post-Enies Lobby Arc  •  Impel Down Arc  •  Marineford Arc  •  Post-War Arc  •  Dressrosa Arc  •  Zou Arc  •  Totto Land Arc
Associated Locations: Baltigo  •  Momoiro Island  •  Newkama Land
Conquered Locations: Centaurea  •  Tequila Wolf
Others: Will of the D.  •  Okama
[v · e · ?]
Devil Fruits
Canon: Gomu Gomu no Mi  •  Bara Bara no Mi  •  Sube Sube no Mi  •  Kilo Kilo no Mi  •  Bomu Bomu no Mi  •  Hana Hana no Mi  •  Doru Doru no Mi  •  Baku Baku no Mi  •  Mane Mane no Mi  •  Toge Toge no Mi  •  Supa Supa no Mi  •  Ori Ori no Mi  •  Bane Bane no Mi  •  Ito Ito no Mi  •  Noro Noro no Mi  •  Doa Doa no Mi  •  Awa Awa no Mi  •  Beri Beri no Mi  •  Sabi Sabi no Mi  •  Shari Shari no Mi  •  Yomi Yomi no Mi  •  Kage Kage no Mi  •  Horo Horo no Mi  •  Suke Suke no Mi  •  Nikyu Nikyu no Mi  •  Ope Ope no Mi  •  Shiro Shiro no Mi  •  Mero Mero no Mi  •  Doku Doku no Mi  •  Horu Horu no Mi  •  Choki Choki no Mi  •  Gura Gura no Mi  •  Woshu Woshu no Mi  •  Fuwa Fuwa no Mi  •  Mato Mato no Mi  •  Buki Buki no Mi  •  Guru Guru no Mi  •  Beta Beta no Mi  •  Hobi Hobi no Mi  •  Bari Bari no Mi  •  Nui Nui no Mi  •  Giro Giro no Mi  •  Ato Ato no Mi  •  Jake Jake no Mi  •  Pamu Pamu no Mi  •  Sui Sui no Mi  •  Ton Ton no Mi  •  Hira Hira no Mi  •  Ishi Ishi no Mi  •  Nagi Nagi no Mi  •  Chiyu Chiyu no Mi  •  Soru Soru no Mi  •  Mira Mira no Mi  •  Pero Pero no Mi  •  Bisu Bisu no Mi
Non-Canon: Goe Goe no Mi  •  Hiso Hiso no Mi  •  Kama Kama no Mi  •  Kachi Kachi no Mi  •  Nemu Nemu no Mi  •  Mini Mini no Mi  •  Atsu Atsu no Mi  •  Noko Noko no Mi  •  Ami Ami no Mi  •  Kopi Kopi no Mi  •  Modo Modo no Mi  •  Mosa Mosa no Mi  •  Peto Peto no Mi  •  Moa Moa no Mi  •  Kyubu Kyubu no Mi  •  Nito Nito no Mi  •  Hore Hore no Mi  •  Gutsu Gutsu no Mi  •  Nuke Nuke no Mi  •  Koro Koro no Mi  •  Jara Jara no Mi  •  Iro Iro no Mi  •  Goru Goru no Mi  •  Raki Raki no Mi
SBS: Samu Samu no Mi  •  Gero Gero no Mi
Canon: Ushi Ushi no Mi, Model: Bison  •  Hito Hito no Mi  •  Tori Tori no Mi, Model: Falcon  •  Inu Inu no Mi, Model: Dachshund  •  Mogu Mogu no Mi  •  Inu Inu no Mi, Model: Jackal  •  Uma Uma no Mi  •  Neko Neko no Mi, Model: Leopard  •  Zou Zou no Mi  •  Inu Inu no Mi, Model: Wolf  •  Ushi Ushi no Mi, Model: Giraffe  •  Hebi Hebi no Mi, Model: Anaconda  •  Hebi Hebi no Mi, Model: King Cobra  •  Hito Hito no Mi, Model: Daibutsu  •  Kame Kame no Mi  •  Sara Sara no Mi, Model: Axolotl  •  Mushi Mushi no Mi, Model: Kabutomushi  •  Mushi Mushi no Mi, Model: Suzumebachi  •  Zou Zou no Mi, Model: Mammoth
Non-Canon: Tori Tori no Mi, Model: Eagle  •  Inu Inu no Mi, Model: Bake-danuki  •  Batto Batto no Mi, Model: Vampire
Related: Rumble Ball  •  Artificial Devil Fruit  •  SMILE
Canon: Moku Moku no Mi  •  Mera Mera no Mi  •  Suna Suna no Mi  •  Goro Goro no Mi  •  Hie Hie no Mi  •  Yami Yami no Mi  •  Pika Pika no Mi  •  Magu Magu no Mi  •  Numa Numa no Mi  •  Gasu Gasu no Mi  •  Yuki Yuki no Mi
Non-Canon: Toro Toro no Mi  •  Pasa Pasa no Mi  •  Ame Ame no Mi
Undetermined Class
Non-Canon: Zuma Zuma no Mi

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