Luffy declares that he will capture Caesar. Law will distract Monet while Chopper finds an antidote for drug. Luffy, Robin and Franky are trying to find a way inside the lab. Tashigi in Smoker's body attacks him while Luffy puts her down easily. The children are trying to free themselves from the chains but Usopp puts them to sleep again. Smoker in Tashigi's body attacks Luffy. Luffy tells him they will fight him later later when he gets his body back. Smiley arrives on the snow side of the island. Zoro, the samurai, Sanji and Brook see some of slime near them wondering what it is.
Caesar arrives and tells them to wait for the experiment to happen again after 4 years from when it first happened until Luffy grabs him, attempting to catch him.
Luffy declares that he will capture Caesar. Law says he will deal with Monet while Chopper tries to find an antidote. Luffy and his group try to find the entrance to the lab. Tashigi and Smoker attack Luffy, with Smoker gaining an advantage until Luffy uses Gear Second and tells Smoker to fight him later when he is at full strength.
Back in the lab, the children start to wake up until Usopp puts them to sleep again. They then see pieces of Smiley falling onto the stolen warship. Franky, not being able to find an entrance, uses his Radical Beam to make an opening. The Marines try attacking it but discover that it emits poison gas when they touch it. One of them tries to burn it but it explodes when it catches on fire, destroying the ship.
Back in the burning lands, Zoro, Sanji, Brook and the samurai see Smiley shooting pieces of itself across the lake. Caesar then appears in the lab, explaining that Smiley was his experiment and that it is weak against water. After his speech, Luffy jumps up and grabs him.